Материалы Всероссийской конференции и школы для молодых ученых памяти Феликса Яновича Дзержинского "Эволюционная и функциональная морфология позвоночных"
This book is a collection of articles dealing with various aspects of grammatical relations and argument structure in the languages of Europe and North and Central Asia (LENCA). Topics covered with respect to individual languages are: split-intransitivity (Basque), causativization (Agul), transitives and causatives (Korean and Japanese), aspectual domain and quantification (Finnish and Udmurt), head-marking principles (Athabaskan languages), and pragmatics (Eastern Khanty and Xibe). Typology of argument-structure properties of ‘give’ (LENCA), typology of agreement systems, asymmetry in argument structure, typology of the Amdo Sprachbund, spatial realtors (Northeastern Turkic), core argument patterns (languages of Northern California), and typology of grammatical relations (LENCA) are the topics of articles based on cross-linguistic data. The broad empirical sweep and the fine-tuned theoretical analysis highlight the central role of argument structure and grammatical relations with respect to a plethora of linguistic phenomena.
The form whose main function is to express indirect commands, called the third person Imperative, Jussive or Exhortative, when compared to the prototypical (second person) Imperative, shows semantic and formal similarities and distinctions at the same time. The study describes formal and functional patterns of Jussive and places this category within the typology of the related categories, such as Imperative and Optative, based on data from six East Caucasian languages (Archi, Agul, Akhvakh, Chechen, Icari and Kumyk). Five formal patterns of Jussive are attested in these languages, including a specialized form, constructions derived from want, from tell him to do and from make him do and the Optative. Jussive forms may express such meanings as third person command, indirect causation, permission, indifference towards the accomplishment of an action and an assumption. While the Jussive is crucially different from the second person Imperative in that it introduces a third participant, this article shows that it is the addressee, not a third person, who is the central participant of a Jussive situation from both formal and functional points of view.
One of the key advances in genome assembly that has led to a significant improvement in contig lengths has been improved algorithms for utilization of paired reads (mate-pairs). While in most assemblers, mate-pair information is used in a post-processing step, the recently proposed Paired de Bruijn Graph (PDBG) approach incorporates the mate-pair information directly in the assembly graph structure. However, the PDBG approach faces difficulties when the variation in the insert sizes is high. To address this problem, we first transform mate-pairs into edge-pair histograms that allow one to better estimate the distance between edges in the assembly graph that represent regions linked by multiple mate-pairs. Further, we combine the ideas of mate-pair transformation and PDBGs to construct new data structures for genome assembly: pathsets and pathset graphs.
Papers about natural protection territories
Many environmental stimuli present a quasi-rhythmic structure at different timescales that the brain needs to decompose and integrate. Cortical oscillations have been proposed as instruments of sensory de-multiplexing, i.e., the parallel processing of different frequency streams in sensory signals. Yet their causal role in such a process has never been demonstrated. Here, we used a neural microcircuit model to address whether coupled theta–gamma oscillations, as observed in human auditory cortex, could underpin the multiscale sensory analysis of speech. We show that, in continuous speech, theta oscillations can flexibly track the syllabic rhythm and temporally organize the phoneme-level response of gamma neurons into a code that enables syllable identification. The tracking of slow speech fluctuations by theta oscillations, and its coupling to gamma-spiking activity both appeared as critical features for accurate speech encoding. These results demonstrate that cortical oscillations can be a key instrument of speech de-multiplexing, parsing, and encoding.
Neuronal nicotinic acetylcholine receptors (NNRs) of the α7 subtype have been shown to contribute to the release of dopamine in the nucleus accumbens. The site of action and the underlying mechanism, however, are unclear. Here we applied a circuit modeling approach, supported by electrochemical in vivo recordings, to clarify this issue. Modeling revealed two potential mechanisms for the drop in accumbal dopamine efflux evoked by the selective α7 partial agonist TC-7020. TC-7020 could desensitize α7 NNRs located predominantly on dopamine neurons or glutamatergic afferents to them or, alternatively, activate α7 NNRs located on the glutamatergic afferents to GABAergic interneurons in the ventral tegmental area. Only the model based on desensitization, however, was able to explain the neutralizing effect of coapplied PNU-120596, a positive allosteric modulator. According to our results, the most likely sites of action are the preterminal α7 NNRs controlling glutamate release from cortical afferents to the nucleus accumbens. These findings offer a rationale for the further investigation of α7 NNR agonists as therapy for diseases associated with enhanced mesolimbic dopaminergic tone, such as schizophrenia and addiction