Glocalization increase has changed the role of regions in the national and world economy. Today regions are becoming independent actors able to compete globally. As for theoretical background, regional development is often based on clustering concept. One of the solutions for competitiveness increase is clusters` internationalization. The paper aims to discover common theoretical ground of clustering concept and internationalization. Their synthesis for analyzing the ways of regional competitiveness increase is a new scientific trend thus lacking substantial theoretical background. The results achieved are the basis for analyzing the problem of clusters` internationalization in order to increase global competitiveness of regions.