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Modeling the metastatic cascade by in vitro microfluidic platforms
Progress in Histochemistry and Cytochemistry. 2015. Vol. 49. No. 4. P. 21–29.
I. A. Khaustov, Yu. A. Safronova, O. E. Chebotareva et al., Applied Biochemistry and Microbiology 2025 Vol. 61 No. 9 P. 1753–1759
Polydimethylsiloxane (PDMS) remains one of the most popular materials for microfluidic chips, but its high gas permeability can lead to the formation of gas bubbles in microchannels, which hampers the reproducibility of experiments in organ-on-a-chip systems. The dependence of the gas permeability of PDMS on the ratio of base to hardener (2.5 : 1, 5 : 1, and ...
Added: December 22, 2025
S. Yu. Paul, Yu. A. Safronova, O. E. Chebotareva et al., Applied Biochemistry and Microbiology 2025 Vol. 61 No. 7 P. 1369–1378
The design and development of a placenta-on-a-chip model is of great importance for various fields of cell biology, especially in studies of the molecular mechanisms of disease pathogenesis and the action of potential drugs. Currently, milling technique is most commonly used to fabricate microfluidic devices from thermoplastics. However, this technology leads to the formation of ...
Added: November 19, 2025
Kalganova A., I. E. Eliseev, Smirnov I. et al., Acta Naturae 2024 Vol. 16 No. 4 P. 15–26
Despite the achievements brought about by high-throughput screening technologies, there is still a lack of effective platforms to be used to search for new antimicrobial drugs. The antimicrobial activity of compounds continues, for the most part, to be assessed mainly using in vitro pathogen cultures, a situation which does not make easy a detailed investigation of the ...
Added: January 28, 2025
Pipiya S., Mirzoeva N., Baranova M. et al., Acta Naturae 2023 Vol. 15 No. 1 P. 74–80
Bacterial infections caused by antibiotic-resistant pathogens pose an extremely serious and elusive problem in healthcare. The discovery and targeted creation of new antibiotics are today among the most important public health issues. Antibiotics based on antimicrobial peptides (AMPs) are of particular interest due to their genetically encoded nature. A distinct advantage of most AMPs is ...
Added: January 20, 2025
Хаустов И. А., Safronova U., Чеботарева О. Е. et al., Биотехнология 2024 Т. 40 № 5 С. 62–69
Polydimethylsiloxane (PDMS) remains one of the most most popular materials for microfluidic chips, but its high gas permeability can lead to the formation of gas bubbles in microchannels, which hampers the reproducibility of experiments in organ-on-a-chip systems. The dependence of the gas permeability of PDMS on the ratio of base to curing agent (2.5 : ...
Added: December 12, 2024
Пауль С. Ю., Safronova U., Чеботарева О. Е. et al., Биотехнология 2024 Т. 40 № 3 С. 77–87
The design and development of a placenta-on-a-chip model is of great importance for various fields of cell biology, especially in studies of the molecular mechanisms of disease pathogenesis and the action of potential drugs. Currently, milling technique is most commonly used to fabricate microfluidic devices from thermoplastics. However, this technology leads to the formation of ...
Added: August 28, 2024
Knyazev E., Nersisyan S., Tonevitsky A., Frontiers in Immunology 2021 Vol. 12 Article 636966
Since 2003, the world has been confronted with three new betacoronaviruses that cause human respiratory infections: SARS-CoV, which causes severe acute respiratory syndrome (SARS), MERS-CoV, which causes Middle East respiratory syndrome (MERS), and SARS-CoV-2, which causes Coronavirus Disease 2019 (COVID-19). The mechanisms of coronavirus transmission and dissemination in the human body determine the diagnostic and ...
Added: September 7, 2021
Wirdatmadja S., Moltchanov D., Balasubramaniam S. et al., IEEE Access 2017 Vol. 5 P. 2417–2429
The advancements in multi-core central processing units have attracted new designs ranging from mechanisms of packing higher number of transistors into the small space, new techniques for communications (e.g., wireless network on chips), or new methodologies for cooling the chip. The latter two design aspects are the focus of this paper, where a microfluidic system ...
Added: March 12, 2018