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Regular version of the site

Article

Cytogenetic Activity of Gold Nanoparticles in Germ and Somatic Cells of 129 Mise with a Nonsense Mutation in the DNA Polymerase Iota Gene

Biology Bulletin. 2018. Vol. 45. No. 2. P. 119-125.
Makarov A. A., Zelenina I., Zakhidov S., Marshak T., Dement'eva O., Rudoy V., Makarova I., Mudzhiri N., Andreeva L.

In this study, we investigated the  cytogenetic effects of single and quadruple exposureof spermatogenic cells and hepatocytesof 129 mise, which have a mutation in the gtnt that encodes DNA polymeraseiota, to ultrasmall gold nanoparticles (GNPs).The combine effects of GNPs and chemical mutagen dipin were evaluated.