Splitting of the ECG Pattern is Not only a Sign of Possible Myocardial Infarction or Cardio Pathology, But one of Many Possible Normal States of the Nonlinear Dynamics of the Heart as Well
The ECG features analysis in a patient born in 1946 led to repeated statement of misdiagnosis, particularly of myocardial infarction. About 2,500 patients’s ECGshave been analyzed for the three-year period of the patient’s observation. A Fourier analysis of the spectra of the ECGs of the patient 2506 allowed to assume that there exists an additional leading center in his myocardium, with a variable start phase of the myocardium relative to the phase
of the fundamental frequency of contractions of the myocardium. Experimental confirmation of this hypothesis is in particular; found in the patient jump-like transition from synchronous phase daily changes in the function dynamics of
the P wave width and the PQ segment to the antiphase ones, which reflects the change in the conditions for triggering the process of myocardial contraction. As a result, the coupling of the two leading frequencies of the myocardium, with a variable phase shift of the triggering, can be expressed both in the extra systoles appearance as well as in unusual cardio cycles not coinciding in the form and phase of cardio cycles of a single ECG. Cluster analysis of the entire set of collected patient’s ECGs in the similarity of their forms revealed 18 separate clusters of similarity. While cluster analysis of the ECG samples in other 4857 patients in most cases led to the identification of only one cluster characteristic for a certain patient’s ECG form. Mathematical modeling of the proposed hypothesis about the presence of more than one leading center of myocardial triggering which resulted in getting model patterns of split ECGs, qualitatively corresponding to the split forms of ECGs observed in the studied patient, confirmed its validity.
Continua Health Alliance is a non-profit, open industry organization of healthcare and technology companies joining together in collaboration to improve the quality of personal healthcare. With more than 200members companies around the world, Continua is dedicated to establishing a system of interoperable personal connected health solutions with the knowledge that extending those solutions into the home fosters independence, empowers individuals and provides the opportunity for truly personalized health and wellness management. When you look at complete list of Continua Certified TM http://www.continuaalliance.org/node/77, you cannot find any ECG device (at the time of writing), but need ECG asa useful screening tool for a variety of cardiac abnormalities. We decided to build the prototype of 3-5-lead ECG with Bluetooth LE and USB interface. The firmware of the device was developed according the ISO/EEE 11073-10406:2011 and this device as a agent can communicate with any manager device on Personal Area Network. The filters of the device (50/60 Hz , low and high pass) are programmable and can be remotely configured. The signals from electrodes can be routed to doctor computer's screen for online diagnostic, can be save in EHR system or sent to special computer with LabView for ECG signal processing with different algorithms. This prototype could be used as a X73 agent for other consumer medical applications.
The extremely important role of information in the modern world has led to the identification of information as an own resource, as important and necessary as energy, financial, raw materials. The needs of society in the collection, storage and processing of information as a commodity have created a new range of services – the information technology market. The volumes of information are growing rapidly, such kind of data volume is called "Big Data», and has been offered for analysis. In order to solve management problems based on the analysis of such data, it is necessary to take into account their heterogeneity, high degree of variation. Therefore, the systematization and grouping of the information obtained makes it possible to improve the quality of the decisions made in the planning and production management tasks. In the process of choosing the grouping methods, the greater dimensionality of the data that affects the processing time of information should be taken into account besides the type of the task in hand. This work presents the results of research of the methods of grouping data for a certain range of practical problems in the processing of large data, as well as the results of solving various practical management problems using various methods
This prototype development explains the challenges encountered during the ISO/IEEE 11073 standard implementation process. The complexity of the standard and the consequent heavy requirements, which have not encouraged software engineers to adopt the standard. The developing complexity evaluation drives us to propose two possible implementation strategies that cover almost all possible use cases and eases handling the standard by non-expert users. The first one is focused on medical devices (MD) and proposes a low-memory and low-processor usage technique. It is based on message patterns that allow simple functions to generate ISO/IEEE 11073 messages and to process them easily. MD act as X73 agent. Second one is focused on more powerful device X73 manager, which do not have the MDs' memory and processor usage constraints. The protocol between Agent and Manager is point-to-point and we can distribute the functionality between devices.
Developed both implementation X73 Agent and Manager will cut developing time for applications based on ISO/EEE 11073.
Summary Objective of the Paper: To find ways to meet the need for specifying terminology and developing a format to describe knowledge in specific subject areas (SA) that will be effective, easily-accessible and clear for both people and programs. This is related to terms, their relationships, models of ECG devices, filters, etc. Key Points: The use of ontology facilitates the following: - a repeated use of knowledge in SA; - a differentiation of the knowledge related to SA from operational knowledge; - a shared general understanding of the information structure among people and programs. An ontology carefully developed for one SA can then be used in other SAs. Moreover, several existent ontologies describing some subdomains of a large SA can be integrated when it is required to create a big ontology. Conclusion: Any SA can have countless ontologies, as each new ontology is just another way to structure concepts and their relationships. Modern doctors must be able to use medical information technologies in their everyday practices, which help them to not waste time on routine calculations and save time and energy for solving current problems. Keywords: electrocardiogram (ECG), telemedicine, ontology, SCP-ECG, OWL.
The creation of software of analyst workplace supporting the mining process large amounts of statistical data of science, education and innovation are discussed in the paper. A hybrid approach, to the integration of classical methods of mathematical correlation analysis, pattern analysis and time series, as well as the interpretation of the results is provided. Particular attention is paid to the business processes to identify trends and changes in indicators, atypical dynamics of indicators and to the definition of «Best Performance» indicators vectors.
The authors proposed and mathematically described model of a new type of the Fermi-Pasta-Ulam recurrence (the FPU auto recurrence) and hypothesized an adequate description of the heart's electrical dynamics within the observed phenomenon. The dynamics of the FPU auto recurrence making appropriate electrical dynamics of the normal functioning of the heart in the form of an electrocardiogram (ECG) was obtained by a computer model study. The model solutions in the form of the FPU auto recurrence – ECG Fourier spectrum were evaluated for resistance to external disturbances in the form of random effects, as well as periodic perturbation at a frequency close to the heart beating rate of about 1 Hz. In addition, in order to simulate the dynamics of myocardial infarction model, studied the effect of the surface area of the myocardium on the stability and shape of the auto recurrence – ECG spectrum. It has been found that the intense external disturbing periodic impacts at a frequency of about 1 Hz lead to a sharp disturbance spectrum shape FPU auto recurrence – ECG structure. In addition, the decrease in the surface of the myocardium by 50% in the model led to the destruction of structures of the auto recurrence – ECG, which corresponds to the state of atrial myocardium. Research models have revealed a hypothetical basis of coronary heart disease in the form of increasing the energy of high-frequency harmonics spectrum of the auto recurrence by reducing the energy of low-frequency harmonic spectrum of the auto recurrence, which ultimately leads to a sharp decrease in myocardial contractility. In order to test the hypothesis has been studied more than 20,000 ECGs both healthy people and patients with cardiovascular disease. As a result of these studies, it was found that the dynamics of the electrical activity of normal functioning of the heart can be interpreted by the display of the detected by authors the FPU auto recurrence, and coronary heart disease is a violation of the energy ratio between the low and high frequency harmonics of the FPU auto recurrence Fourier spectrum equal to the ECG spectrum. Thus, the hypothesis has been confirmed.
This proceedings publication is a compilation of selected contributions from the “Third International Conference on the Dynamics of Information Systems” which took place at the University of Florida, Gainesville, February 16–18, 2011. The purpose of this conference was to bring together scientists and engineers from industry, government, and academia in order to exchange new discoveries and results in a broad range of topics relevant to the theory and practice of dynamics of information systems. Dynamics of Information Systems: Mathematical Foundation presents state-of-the art research and is intended for graduate students and researchers interested in some of the most recent discoveries in information theory and dynamical systems. Scientists in other disciplines may also benefit from the applications of new developments to their own area of study.
This volume presents new results in the study and optimization of information transmission models in telecommunication networks using different approaches, mainly based on theiries of queueing systems and queueing networks .
The paper provides a number of proposed draft operational guidelines for technology measurement and includes a number of tentative technology definitions to be used for statistical purposes, principles for identification and classification of potentially growing technology areas, suggestions on the survey strategies and indicators. These are the key components of an internationally harmonized framework for collecting and interpreting technology data that would need to be further developed through a broader consultation process. A summary of definitions of technology already available in OECD manuals and the stocktaking results are provided in the Annex section.