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Self-face viewing attenuates cardiac modulation of corticospinal excitability

FRONTIERS IN SIGNAL PROCESSING. 2026. Vol. 6. Article 1776807.
Makarova M., Fedosov N., Mikhailova I., Nikolaeva M., Ossadtchi A., Tumialis A., Volodina M.

Introduction: 

While self-referential attention is thought to enhance interoceptive sensitivity, its effect on cardiac modulation of corticospinal excitability remains unexplored. This pilot study investigated how viewing one’s own face (self-face processing) modulates the cardiac-phase coupling of motor output and whether this heart-brain coupling depends on interoceptive accuracy (heartbeat perception).

Methods: 

In 15 healthy adults, motor-evoked potentials (MEPs) were elicited via transcranial magnetic stimulation (TMS) at three fixed time points following the R-peak (0, 250, and 500 m) during presentation of either self-face or other-face pictures. A Modulation Index was derived from log-transformed MEPs to quantify cardiac-phase modulation strength. Interoceptive accuracy was assessed via a heartbeat-counting task.

Results: 

Contrary to the hypothesis that self- face viewing would enhance cardiac–motor coupling through inward attentional focus, self-face processing significantly reduced the overall magnitude of cardiac-phase modulation. This attenuation was most pronounced at 0 m and 250 m post-R-peak, corresponding to systolic phase. Across conditions, higher interoceptive accuracy predicted stronger modulation, though this relationship showed a tendency toward attenuation during self-face viewing (interaction p = 0.059).

Discussion: 

The results of this pilot TMS study suggest that, in a task requiring explicit evaluation of facial stimuli, self-face viewing acts as a potent exteroceptive stimulus that diverts attention away from interoceptive signals, thereby weakening the cardiac-cycle influence on motor excitability. These findings highlight the context-dependency of self-processing effects and suggest a possible link between HCT-based interoceptive accuracy and heart-brain- body coupling.

Research target: Medical Technologies Biology Basic Medicine Psychology
Language: English
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Keywords: Transcranial magnetic stimulation (TMS)транскраниальная магнитная стимуляция (ТМС)interoceptive accuracycardiac modulation of corticospinal excitabilityheart-brain couplingmotor-evoked potentials (MEPs)self-face processingкардиальная модуляция кортикоспинальной возбудимостисвязь «сердце—мозг»интероцептивная точностьвосприятие изображений собственного лица
Publication based on the results of:
Multidisciplinary study of behavior and decision-making in health population and patients using behavioral, economic, neurocognitive, neuroeconomic, neurocomputational and neural network approaches (2025)
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