Распространенность анемии и ее ассоциации с другими гериатрическими синдромами у лиц старше 65 лет: данные российского эпидемиологического исследования ЭВКАЛИПТ
Терапевтический архив 2022 Т. 94 № 1 С. 24-31
Background. A low hemoglobin level in older adults impairs cognitive ability and functional status and associates with risk of falls and fractures, sarcopenia, malnutrition, depression, frailty, and decreased autonomy. Epidemiological data on the anemia prevalence in the geriatric population in our country is not available. Aim. To assess the prevalence of anemia and analyze its associations ...
Added: March 18, 2022
Journal of Neural Engineering 2021 Vol. 18 Article 026019
Abstract Objective. Brain–computer interfaces (BCIs) decode information from neural activity and send it to external devices. The use of Deep Learning approaches for decoding allows for automatic feature engineering within the specific decoding task. Physiologically plausible interpretation of the network parameters ensures the robustness of the learned decision rules and opens the exciting opportunity for automatic knowledge ...
Added: January 24, 2022
GATA1 mutation analysis and molecular landscape characterization in acute myeloid leukemia with trisomy 21 in pediatric patients
International Journal of Laboratory Hematology 2021 Vol. 43 No. 4
Introduction: Accurate detection of GATA1 mutation is highly significant in patients with acute myeloid leukemia (AML) and trisomy 21 as it allows optimization of clinical protocol. This study was aimed at (a) enhanced search for GATA1 mutations; and (b) characterization of molecular landscapes for such conditions. Methods: The DNA samples from 44 patients with ...
Added: December 21, 2021
Grain-based dietary background impairs restoration of blood flow and skeletal muscle during hindlimb ischemia in comparison with low-fat and high-fat diets
FRONTIERS IN NUTRITION 2022 No. 8 Article 809732
Background: Among vascular pathologies associated with obesity peripheral artery disease (PAD) occupies the important position. In clinical practice nutritional interventions are recommended for PAD patients. In this study we investigate how the different dietary backgrounds affect the regeneration rate of ischemic hindlimb in mice. Methods: Male C57BL/6J mice were housed on three types of diet: low-fat ...
Added: December 20, 2021
Обзор психофизиологических и психотерапевтических исследований стресса с помощью технологий виртуальной реальности
Журнал высшей нервной деятельности им. И.П. Павлова 2021
Данный обзор посвящён применению технологий виртуальной реальности в психофизиологии и психотерапии стресса. Рассмотрены исследования, применяющие виртуальную реальность, как для введения испытуемых в состояние стресса, так и для помощи в снижении стрессовых реакций. Описаны методики, разработанные для лечения пациентов, страдающих расстройствами, связанными со стрессом (в частности, ПТСР, фобии). Во многих случаях снижение стрессовых реакций с помощью ...
Added: December 14, 2021
Послеоперационная мозговая дисфункция в раннем и отсроченном послеоперационном периоде при каротидной эндартерэктомии
Госпитальная медицина: наука и практика 2020 Т. 1 № 4 С. 5-10
Changes in the cognitive status of patients after reconstructive operations in the basin of the carotid arteries are not a rare complication of the course of the early postoperative period, and may also have the character of delayed and persistent changes. Age-dependent neurodegenerative changes, which are essentially a natural sign of brain aging, can trigger ...
Added: December 10, 2021
Госпитальная медицина: наука и практика 2020 Т. 1 № 3 С. 5-10
The typical clinical picture of COVID-19 disease is represented by manifestations at the respiratory level, with bilateral atypical pneumonia with significant respiratory impairment due to diffuse alveolar damage, but SARS-CoV-2 can also infect other organs and cell types, including the nervous system. Neurological disorders occur in about a third of COVID-19 patients and are associated ...
Added: December 10, 2021
‘Moderate global aphasia’: A generalized decline of language processing caused by glioma surgery but not stroke
Brain and Language 2022 Vol. 224 Article 105057
Unlike stroke, neurosurgical removal of left-hemisphere gliomas acts upon a reorganized language network and involves brain areas rarely damaged by stroke. We addressed whether this causes the profiles of neurosurgeryand stroke-induced language impairments to be distinct. K-means clustering of language assessment data (neurosurgery cohort: N = 88, stroke cohort: N = 95) identified similar profiles ...
Added: December 8, 2021
Immunity 2020 Vol. 53 P. 1245-1257
Understanding the hallmarks of the immune response to SARS-CoV-2 is critical for fighting the COVID-19 pandemic. We assessed antibody and T cell reactivity in convalescent COVID-19 patients and healthy donors sampled both prior to and during the pandemic. Healthy donors examined during the pandemic exhibited increased numbers of SARS-CoV-2-specific T cells, but no humoral response. Their ...
Added: December 7, 2021
Medical News of North Caucasus 2018 Vol. 13 No. 1 P. 259-271
Abstract The first Russian expert consensus on the quantitative evaluation of the treatment adherence: pivotal issues, algorithms and recommendations approved by the XII National Congress of physicians (Moscow, 22-24 November, 2017). © 2018 Stavropol State Medical University. All rights reserved. ...
Added: November 18, 2021
Новые концепции в комплексном лечении пациентов с травмой спинного мозга, включающие реконструктивную микрохирургию и последующую реабилитацию
Вестник Российской академии медицинских наук 2008 № 8 С. 29-34
This work is been based upon the experience of performing 100 reconstructive microsurgical operations with transplantation of combined vascular-neural autografts, in 24 cases - with introduction cellular material into zone of transplantation. The complex approach aimed to creating optimal conditions for the functional regeneration of the spinal cord (SC), including neurosurgical methods restoring anatomical integrity ...
Added: November 16, 2021
HIF-Dependent NFATC1 Activation Upregulates ITGA5 and PLAUR in Intestinal Epithelium in Inflammatory Bowel Disease
Frontiers in Genetics 2021 Vol. 12 Article 791640
Intestinal epithelial cells exist in physiological hypoxia, leading to hypoxia-inducible factor (HIF) activation and supporting barrier function and cell metabolism of the intestinal epithelium. In contrast, pathological hypoxia is a common feature of some chronic disorders, including inflammatory bowel disease (IBD). This work was aimed at studying HIF-associated changes in the intestinal epithelium in IBD. ...
Added: November 11, 2021
Frontiers in Psychiatry 2021 P. 1-14
Psychosocial stress is a significant public health problem inducing consequences for quality of life. Results about the use of dehydroepiandrosterone (DHEA) as a biomarker of acute stress are conflicting. We conducted a systematic review and meta-analysis to demonstrate that DHEA levels could be a biomarker of stress. ...
Added: November 1, 2021
Background: Previous studies have shown that individuals with aphasia have impairments in switching attention compared to healthy controls. However, there is insufficient information about the characteristics of switching attention within one task and whether attention deficits vary depending on aphasia type and lesion location. We aimed to address these knowledge gaps by investigating characteristics of ...
Added: October 29, 2021
Frontiers in Genetics 2021 Article 638191
We propose a method for generating an electrocardiogram (ECG) signal for one cardiac cycle using a variational autoencoder. Our goal was to encode the original ECG signal using as few features as possible. Using this method we extracted a vector of new 25 features, which in many cases can be interpreted. The generated ECG has ...
Added: October 29, 2021
Психологические особенности религиозной личности, влияющие на реабилитационную работу с больными, страдающими психическими расстройствами
Психиатрия 2016 Т. 70 № 2 С. 50-54
Background. Religious manifestations of mentally disordered individuals seem to be regarded as some «refracted» common peculiarities of mentally normal believers. The objective was to describe general psychological features of religious personality significant for rehabilitation of mental patients. Material and methods. Some psychological peculiarities of the religious personality are regarded compared with normal manifestations of religiosity from those ...
Added: October 2, 2021
Культурно-историческая психология 2019 Т. 15 № 4 С. 56-67
The purpose of the study described in the article is to elicit value and meaning elements and to describe their structure in mentally ill patients with the religious outlook. The assumptions that the value and meaning system (VMS) of believing patients and non-believing ones differ are put forward. Four groups of subjects participate in the ...
Added: September 29, 2021
Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019
The Lancet 2021 Vol. 398 No. 10303 P. 870-905
Background Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child ...
Added: September 24, 2021
Endocytosis and Transcytosis of SARS-CoV-2 Across the Intestinal Epithelium and Other Tissue Barriers
Frontiers in Immunology 2021 Vol. 12 Article 636966
Since 2003, the world has been confronted with three new betacoronaviruses that cause human respiratory infections: SARS-CoV, which causes severe acute respiratory syndrome (SARS), MERS-CoV, which causes Middle East respiratory syndrome (MERS), and SARS-CoV-2, which causes Coronavirus Disease 2019 (COVID-19). The mechanisms of coronavirus transmission and dissemination in the human body determine the diagnostic and ...
Added: September 7, 2021
Фундаментальная и прикладная математика 2020 Т. 23 № 2 С. 37-56
Рассматривается задача построения триангуляции внутренней поверхности аорты и коронарных артерий. Это необходимо для создания гидродинамической модели крово-снабжения сердца. Исходными данными являются поперечные томографические срезы сердца конкретного пациента толщиной0,5мм. Триангуляцию аорты и коронарных артерий планируется использовать для расчёта кровотока в программном комплексе FlowVision, предназначенном для моделирования трёхмерных течений жидкости и га-за. Результаты моделирования планируется применять в практической медицине для диагностики ишемии ...
Added: August 16, 2021
Multimodal DTI-TMS assessment of the motor system in patients with chronic ischemic stroke / Cold Spring Harbor Laboratory. Series http://dx.doi.org/ "BioRxiv". 2019. No. 2019.12.24.886754.
Background and Purpose Despite the continuing efforts in multimodal assessment of the motor system after stroke, conclusive findings on the complementarity of functional and structural metrics of the corticospinal tract (CST) integrity and the role of the contralesional hemisphere are still missing. The aim of this work was to find the best combination of the motor ...
Added: January 29, 2020