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Estimating the timing of multiple admixture events using 3-locus Linkage Disequilibrium
Cold Spring Harbor Laboratory
,
2021.
Liang M., Shishkin M., Mikhailova A. et al., PLoS Genetics 2022 Vol. 18 No. 7 Article e1010281
Estimating admixture histories is crucial for understanding the genetic diversity we see in present-day populations. Allele frequency or phylogeny-based methods are excellent for inferring the existence of admixture or its proportions. However, to estimate admixture times, spatial information from admixed chromosomes of local ancestry or the decay of admixture linkage disequilibrium (ALD) is used. One ...
Added: August 13, 2022
Svedberg J., Shchur V., Reinman S. et al., / Cold Spring Harbor Laboratory. Series 005140 "Biorxiv". 2020.
Adaptive introgression - the flow of adaptive genetic variation between species or populations - has attracted significant interest in recent years and it has been implicated in a number of cases of adaptation, from pesticide resistance and immunity, to local adaptation. Despite this, methods for identification of adaptive introgression from population genomic data are lacking. ...
Added: October 17, 2020
Mahdavi A., Qin Y., Aubry A. -. et al., / Cold Spring Harbor Laboratory. Series New Results "BioRxiv". 2019.
Schizophrenia is a chronic debilitating disease. Sleep disturbances associated with a reduction in spindles are observed as warning signs prior to the first psychotic episode. Every spindle is a short-lasting (~0.5 s) set of bioelectric sinusoidal waves at the frequency of 10-16 Hz generated within the thalamus. Sleep spindles, easily identifiable in a scalp electroencephalogram, ...
Added: November 11, 2019
Svedberg J., Shchur V., Reinman S. et al., Molecular Biology and Evolution 2021 Vol. 38 No. 5 P. 2152-2165
Adaptive introgression—the flow of adaptive genetic variation between species or populations—has attracted significant interest in recent years and it has been implicated in a number of cases of adaptation, from pesticide resistance and immunity, to local adaptation. Despite this, methods for identification of adaptive introgression from population genomic data are lacking. Here, we present Ancestry_HMM-S, ...
Added: May 21, 2021
Springer, 2018
This book constitutes the joint refereed proceedings of the 18th International Conference on Next Generation Wired/Wireless Advanced Networks and Systems, NEW2AN 2018, the 11th Conference on Internet of Things and Smart Spaces, ruSMART 2018. The 64 revised full papers presented were carefully reviewed and selected from 186 submissions. The papers of NEW2AN focus on advanced ...
Added: October 6, 2018
Molotkov S., Laser Physics Letters 2019 Vol. 16 P. 105205
A proof of the secrecy of the quantum key distribution through an untrusted node is given.
The use of entropy uncertainty relations allows us to obtain an exact solution for the length
of the secret key in the single-photon case. Comparison with the exact solution for the BB84
protocol is made and the principal difference in the logical ...
Added: December 4, 2019
Nikolaevskiy N., Пилипчук С. Ф., Спасский Я. Б., Логистика и управление цепями поставок 2017 № 3 С. 21-30
The development of the domestic economy from the beginning of the 21st century is characterized by the growth of energy resources export volumes, including coal. That circumstance determined the increased demand for the design, research and modernization of export bulk cargo terminals. Growth of customers requirements and outdated standards, regulations and specifications define the need ...
Added: October 6, 2018
Уральский государственный педагогический университет, 2019
Конференция призвана распространить методы и средства имитационного моделирования для решения научных и практических задач, активизировать творческую деятельность и укрепить научно-производственный потенциал Российской Федерации ...
Added: March 9, 2021
Shkurnikov M. Yu., Nersisyan S. A., Osepyan A. S. et al., Doklady Biochemistry and Biophysics 2020 Vol. 493 No. 1 P. 208-210
Human colorectal adenocarcinoma cell line Caco-2 is often used as a model of healthy intestinal epithelium, in particular, in miRNA studies. The work of the enzymes Drosha and Dicer is an integral part of the process of miRNA formation. Inaccuracies in the work of these enzymes lead to a change in the nucleotide sequences of ...
Added: October 13, 2020
Springer, 2017
This book constitutes the joint refereed proceedings of the 17th International Conference on Next Generation Wired/Wireless Advanced Networks and Systems, NEW2AN 2017, the 10th Conference on Internet of Things and Smart Spaces, ruSMART 2017. The 71 revised full papers presented were carefully reviewed and selected from 202 submissions. The papers of NEW2AN focus on advanced ...
Added: October 6, 2018
Molotkov S.N., Laser Physics Letters 2019 Vol. 16 P. 035203
The analysis of a new two-parametric quantum cryptography protocol is presented. A
fundamentally new feature of the protocol is that the detection of the eavesdropper occurs not
only by the number of errors on the receiving side, but also by the number of photocounts in
the control time slots. The second feature of this protocol is the fact ...
Added: December 4, 2019
S. A. Nersisyan, M. Yu. Shkurnikov, E. N. Knyazev, Doklady Biochemistry and Biophysics 2020 Vol. 493 No. 1 P. 205-207
One of the main complications of pregnancy and causes of maternal and perinatal mortality is preeclampsia. The pathophysiology of preeclampsia is associated with the development of placenta and fetal hypoxia and secretion of a number of effective molecules. The human choriocarcinoma cell line BeWo b30 is often used as a model of the placental barrier. ...
Added: October 13, 2020
Margaryan A., Lawson D. J., Sikora M. et al., Nature 2020 Vol. 585 No. 7825 P. 390-396
The maritime expansion of Scandinavian populations during the Viking Age (aboutad 750-1050) was a far-flung transformation in world history(1,2). Here we sequenced the genomes of 442 humans from archaeological sites across Europe and Greenland (to a median depth of about 1x) to understand the global influence of this expansion. We find the Viking period involved ...
Added: October 30, 2020
СПб. : ГУМРФ имени адмирала С.О. Макарова, 2016
Сборник материалов конференции посвящен вопросам логистики. Рассматриваются теоретические аспекты логистики, вопросы практического применения логистических принципов, преподавания логистики в высших учебных заведениях. Издание предназначено для преподавателей вузов, для специалистов, чья деятельность связана с логистикой, и для всех интересующихся этой проблематикой. ...
Added: October 5, 2018
Садовничий В. А., Akaev A., Korotayev A. et al., М. : Издательская группа URSS, 2017
В коллективной монографии представлены результаты исследований, проведенных в рамках проекта РНФ №14-11-00634 «Математические методы прогнозирования мирового и странового социально-экономического развития». Целью проекта является разработка методологии, математических методов и моделей для анализа и прогнозирования современных макротенденций и циклов экономической, демографической, политической, социальной, культурной и технологической мировой, региональной и национальной динамики в интересах научного обеспечения стратегического планирования в Российской Федерации.
Первая ...
Added: October 23, 2018
Flegontov P., Kassian A., Thomas M. et al., Genome Biology and Evolution 2016 Vol. 8 No. 7 P. 2259-2265
In a recent interdisciplinary study, Das et al. have attempted to trace the homeland of Ashkenazi Jews and of their historical language, Yiddish (Das et al. 2016. Localizing Ashkenazic Jews to Primeval Villages in the Ancient Iranian Lands of Ashkenaz. Genome Biol Evol. 8:1132–1149). Das et al. applied the geographic population structure (GPS) method to ...
Added: October 21, 2017
Butovskaya M., Annals of Human Genetics 2018 Vol. 82 No. 6 P. 407-414
The key regulator in the control of aggressive behavior is dopamine receptors. Association of variants in these genes with aggression has been shown in modern populations. However, these studies have not been conducted in traditional cultures. The aim of our study was to investigate population features in distributions of allele and genotype frequencies of DRD2 rs1800497, DRD4 120 bp Ins, ...
Added: September 20, 2018
Molotkov S.N., Laser Physics Letters 2019 Vol. 16 No. 7 P. 075203
A simple and effective fiber implementation of the BB84 protocol is proposed, which does not
use phase modulators at the receiving side and do not require adjustment of the polarization
state at the output of the communication channel. The implementation of the protocol permits
to prove of the secrecy of keys based on the fundamental entropic uncertainty relations. ...
Added: December 4, 2019
Shchur V., Brandt D. Y., Ilina A. et al., / Cold Spring Harbor Laboratory. Series 005140 "Biorxiv". 2022.
The estimation of effective population sizes (Ne) through time is of fundamental interest in population genetics, but the interpretation of Ne as the effective number of breeding individuals in the population is challenged by the effect of population struc- ture. In fact, variation in Ne reported in many studies may be a consequence of changes in migration rates between ...
Added: June 17, 2022
[б.и.], 2018
В сборнике рассматриваются способы изучения возникающих и развивающихся явлений. Первостепенное внимание уделяется использованию морфологических и семиотических методов. Обсуждаются проблемы формирования Вселенной и биосферы, человечества, когнитивных и научно-исследовательских способностей людей, а также создания новых методов и методик научных исследований, рационализации и обновления уже сложившихся. Уделяется внимание методологическим синтезам, сочетанию морфологических и семиотических методов, развитию в современных условиях биосемиотики, биосоциальной ...
Added: November 12, 2018
Switzerland : Springer, 2020
This book introduces a 'Big History' perspective to understand the acceleration of social, technological and economic trends towards a near-term singularity, marking a radical turning point in the evolution of our planet. It traces the emergence of accelerating innovation rates through global history and highlights major historical transformations throughout the evolution of life, humans, and civilization. ...
Added: January 27, 2020
Knyazev E. N., Paul S. Yu., Tonevitsky A. G., Doklady Biochemistry and Biophysics 2021 Vol. 499 No. 1 P. 251-256
Choriocarcinoma cells BeWo b30 are used to model human placental trophoblast hypoxia using cobalt (II) chloride and hydroxyquinoline derivative (HD) as chemical inducers of hypoxia-inducible factor (HIF). In this study, it was shown that both substances activate the hypoxic pathway and the epithelial–mesenchymal transition and inhibit the pathways of cell proliferation. However, CoCl2 caused activation of ...
Added: August 26, 2021
Nikolaevskiy N., Grigorev M., Логистика и управление цепями поставок 2018 № 5 С. 29-37
The results of the information technologies intensive development and implementation processes, recently defined as digitalization, were the basis of the significant changes in the domestic economy. At the same time, it is important to understand that digitalization process require an appropriate response in order to create an environment, which promote to development of strategically valuable ...
Added: November 30, 2018
Knyazev E. N., Paul S. Yu., Bulletin of Russian State Medical University 2021 No. 2 P. 11-17
In humans, trophoblast hypoxia during placental development can be a cause of serious pregnancy complications, such as preeclampsia and fetal growth restriction. The pathogenesis of these conditions is not fully clear and may be associated with changed expression of some genes and regulatory molecules, including miRNA, in trophoblast cells. The aim of this study was ...
Added: June 18, 2021