Картирование потенциально артефакт-значимых сосудов мозга с помощью МР-последовательности SWI (susceptibility weighted imaging): автоматизированный протокол
Brain mapping is a complex scientific and practical challenge. One of the most important non-invasive methods of brain mapping is functional MRI (fMRI). FMRI has some limitations because of false positive BOLD-signal changes in region-of-interest draining veins. We can localize veins and venules after fMRI brain mapping, for example with MR-sequence Susceptibility Weighted Imaging (SWI; Haacke, Ye, 2004), in order to understand whether fMRI results are influenced by vein signals or not. We worked out a computer-aided protocol for individual veins and venules localization on the basis of SWI images for users of the SPM12 software package designed for the analysis of fMRI. We used the method described by Wilson (2014) with some modifications. The protocol was tested on data from 48 healthy volunteers.