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Regular version of the site
Of all publications in the section: 627
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Article
Thornbush M., Golubchikov O., Bouzarovski S. Sustainable Cities and Society. 2013. Vol. 9. P. 1-9.

This paper examines recent literature on achieving sustainable cities that incorporate a combined mitigation–adaptation approach towards improved urban resilience as a way of future-proofing. A multidisciplinary approach, which integrates scientific as well as ecopolitical frameworks, is found to benefit this sustainability discourse.

Added: Oct 9, 2014
Article
Ilina I. N., Голубчиков Ю. Н., Маркова О. И. et al. International Journal of Sustainable Development and World Ecology. 2016. Vol. 23. No. 5. P. 1-10.

The article discusses the modern periglacial environment of high-latitude and high-altitude regions that extends from the cold limits of forest to the snowline. Within a compact space, several sharply contrasting mountain landscape belts interchange. Living organisms there are particularly affected by cosmic and random-destructive forces. Precisely in these areas, various global geographical, geological, and biological problems are manifested most vividly. The upper limits of agriculture and their importance for high-altitude areas in the main mountain systems of the world are considered. Tourism changes the periglacial environment approach paradigm from the use- and risk-management perspective to the axiological, with attractive categories, angle.

Added: Aug 23, 2016
Article
Ермоленко Г. В., Proskuryakova L. N., Ермоленко Б. В. Foresight. 2017. Vol. 19. No. 5. P. 528-540.

Purpose – The purpose of the study is to show the technical potentials of a variety of renewable energy sources in Russia, as well as benefits from their deployment including hydrocarbon savings, emission reduction and lower energy cost. Design/methodology/approach – In the paper, Russia is compared with other countries in terms of actual installed capacity and its dynamics, actual and projected share of renewables in the energy mix. The authors offer calculations of the technical potentials (fuel, heat energy, electrical energy, resource saving and environmental) of renewables (solar PV, wind, biomass, geothermal, low-grade heat, small hydro), identify social and economic preconditions and key effects of their deployment. Findings – The paper features calculations on the renewable energy technology potential, based on the data by Andreenko et al. (2015), authors’ calculations and statistical data. This study proves that the cumulative technical potential of the renewables in Russia amounts to 133,935 million units of oil equivalent. This study also offers assessments of oil fuel, black coal and natural gas savings that may be achieved by replacing fossil fuels with renewables; assessments of avoided air pollution calculated as CO- and CO2-equivalents. Originality/value – The paper fills in the gap of comprehensive assessments of renewable energy potentials in Russia and a variety of effects that their deployment may entail, based on a single integral methodology. The authors offer a new evaluation of existing and future renewable energy potentials, overcoming the methodological and data constraints faced by previous similar studies. The up-to-date, comprehensive and accurate data will help make the right investment and policy choices.

Added: Sep 25, 2017
Article
Lavrenov S., Luzikov Y., Bykov E. et al. Bioorganic and Medicinal Chemistry. 2010. Vol. 18. No. 18. P. 6905-6913.

Novel derivatives of tris(indol-3-yl)methane and tris(indol-3-yl)methylium salts with the alkyl substituents at the N-atoms of the indole rings were synthesized. An easy substitution of indole rings in trisindolylmethanes for other indoles under the action of acids is demonstrated, and the mechanism of substitution is discussed. To obtain trisindolylmethylium salts, the environmentally safe method of oxidation of trisindolylmethanes with air oxygen in acidic conditions was developed. Tris(1-alkylindol-3-yl)methanes and tris(1-alkylindol-3-yl)methylium salts represent three-bladed molecular propellers whose physico-chemical and biological properties strongly depend on the N-alkyl substituent. The cytotoxicity of novel compounds increased with the number of C atoms in the alkyl chains, with optimal number n = 3-5 whereas the derivatives with longer side chains were less cytotoxic. The most potent novel compounds killed human tumor cells at nanomolar-to-submicromolar concentrations, being one order of magnitude more potent than the prototype antibiotic turbomycin A [tris(indol-3-yl)methylium salt]. Apoptosis in HCT116 colon carcinoma cell line induced by tris(1-pentyl-1H-indol-3-yl)methylium methanesulfonate was detectable at concentrations tolerable by normal blood lymphocytes. Thus, N-alkyl substituted tris(1-alkylindol-3-yl)methylium salts emerge as perspective anticancer drug candidates. 

Added: Jul 14, 2015
Article
Shchekotikhin A., Glazunova V.A., Dezhenkova L. et al. Bioorganic and Medicinal Chemistry. 2009. Vol. 17. No. 5. P. 1861-1869.

We developed the synthesis of a series of thiophene-fused tetracyclic analogues of the antitumor drug ametantrone. The reactions included nucleophilic substitution of methoxy groups in 4,11-dimethoxyanthra[2,3-b]thiophene-5,10-diones with ethylenediamines, producing the derivatives of 4,11-diaminoanthra[2,3-b]thiophene-5,10-dione in good yields. Several compounds showed marked antiproliferative potency against doxorubicin-selected, P-glycoprotein-expressing tumor cells and p53-/- cells. The cytotoxicity of some novel compounds for P-glycoprotein-positive cells is highly dependent on N-substituent at the terminal amino group of ethylenediamine moiety. The cytotoxic potency of selected compounds correlated with their ability to attenuate the functions of topoisomerase I and telomerase, strongly suggesting that these enzymes are the major targets of antitumor activity of anthra[2,3-b]thiophene-5,10-dione derivatives.

Added: Jul 14, 2015
Article
Shchekotikhin A., Glazunova V.A., Dezhenkova L. et al. European Journal of Medicinal Chemistry. 2014. Vol. 86. P. 797-805.

A series of new 3-aminomethyl-411-dihydroxynaphtho[2,3-f]indole-5,10-diones 6-13 bearing the cyclic diamine in the position 3 of the indole ring was synthesized. The majority of new compounds demonstrated a superior cytotoxicity than doxorubicin against a panel of mammalian tumor cells with determinants of altered drug response, that is, Pgp expression or p53 inactivation. For naphtho[2,3-f]indole-5,10-diones 6-9 bearing 3-aminopyrrolidine in the side chains, the ability to bind double-stranded DNA and inhibit topoisomerases 1 and 2 mediated relaxation of supercoiled DNA were demonstrated. Only one isomer, (R)-4,11-dihydroxy-3-((pyrrolidin-3-ylamino)methyl)-1H-naphtho[2,3-f]indole-5,10-dione (7) induced the formation of specific DNA cleavage products similar to the known topoisomerase 1 inhibitors camptothecin and indenoisoquinoline MJ-III-65, suggesting a role of the structure of the side chain of 3-aminomethylnaphtho[2,3-f]indole-5,10-diones in interaction with the target. Compound 7 demonstrated an antitumor activity in mice with P388 leukemia transplants whereas its enantiomer 6 was inactive. Thus, 3-aminomethyl derivatives of 4,11-dihydroxynaphtho[2,3-f]indole-5,10-dione emerge as a new prospective chemotype for the search of antitumor agents. © 2014 Elsevier Masson SAS.

Added: Jul 14, 2015
Article
Kertesz-Farkas A., Noble W. Journal or Proteome Research. 2015. Vol. 14. No. 8. P. 3027-3038.
Added: Sep 25, 2015
Article
Chugunov A., Volynsky P., Krylov N. et al. Scientific Reports. 2016. Vol. 6. No. 33112. P. 1-16.

Heat-activated transient receptor potential channel TRPV1 is one of the most studied eukaryotic proteins involved in temperature sensation. Upon heating, it exhibits rapid reversible pore gating, which depolarizes neurons and generates action potentials. Underlying molecular details of such effects in the pore region of TRPV1 is of a crucial importance to control temperature responses of the organism. Despite the spatial structure of the channel in both open (O) and closed (C) states is known, microscopic nature of channel gating and mechanism of thermal sensitivity are still poorly understood. In this work, we used unrestrained atomistic molecular dynamics simulations of TRPV1 (without N- and C-terminal cytoplasmic domains) embedded into explicit lipid bilayer in its O- and C-states. We found that the pore domain with its neighboring loops undergoes large temperature-dependent conformational transitions in an asymmetric way, when fragments of only one monomer move with large amplitude, freeing the pore upon heating. Such an asymmetrical gating looks rather biologically relevant because it is faster and more reliable than traditionally proposed "iris-like" symmetric scheme of channel opening. Analysis of structural, dynamic, and hydrophobic organization of the pore domain revealed entropy growth upon TRPV1 gating, which is in line with current concepts of thermal sensitivity.

Added: Nov 11, 2016
Article
Kychkin A., Krysin N., Krivoshchekov S. et al. Neftyanoe Khozyaistvo - Oil Industry. 2016. No. 12. P. 136-139.

The article describes testing of dispatching module of developing telemetry system of well borehole trajectory monitoring for well drilling with use of rotary steerable system. A scheme of reliability evaluation and a stand for load testing of program apparatus complex of surface equipment are discussed. A scheme includes communication controller, input module, and operator’s station and power supplies. These functional units, connected in series, create dispatching system with performance parameters that may be evaluated by continuous formation, sending, processing and saving of recorded data on well state. A well is modeled on regimes close to real production on a drill site. Load testing on stand consist of formation and sending of data array from communication controller to an operator’s station. An array carries time label with date and time, coordinates in metrical notation system and attributes – data about odometry, azimuthal angles and temperature. Modeling signals on well trajectory and additional attribute parameter, arrived to dispatching module, provide automated test regime of program apparatus complex of surface equipment of dispatching module and allow revealing elements that decrease general reliability of entire system of telemetry monitoring on development stage. During continuous load testing failures of program code of operator’s station are found. Border conditions when a system maintains reliable state during long time and parameters of information transmission rate are determined. Based on scheme of series connection reliability of dispatching system main parameters of reliability are calculated.

Added: Nov 25, 2018
Article
Yemelina Natalya K., Kudryavtsev S. S., Yemelin P. V. Safety and Health at Work. 2018. Vol. 9. No. 1. P. 30-41.

Background: The purpose of the work is to develop a system that allows processing of information for analysis and industrial risk management, to monitor the level of industrial safety and to perform necessary measures aimed at the prevention of accidents, casualties, and development of professional diseases for effective management of industrial safety at hazardous industrial sites. Methods: Risk assessment of accidents and incidents is based on expert evaluations. Based on the lists of criteria parameters and their possible values, provided by the experts, a unified information and analytical database is compiled, which is included in the final interrogation questionnaires. Risk assessment of industrial injuries and occupational diseases is based on statistical methods. Results: The result of the research is the creation of Guidelines for risk management on hazardous industrial sites of the Republic of Kazakhstan. The Guidelines determine the directions and methods of complex assessment of the state of industrial safety and labor protection and they could be applied as methodological basis at the development of preventive measures for emergencies, casualties, and incidents at hazardous industrial sites. Conclusion: Implementation of the information-analytical system of risk level assessment allows to analyze the state of risk of a possible accident at industrial sites, make valid management decisions aimed at the prevention of emergencies, and monitor the effectiveness of accident prevention measures.

Added: Apr 20, 2019
Article
Linder D. P., Silvernail N. J., Barabanschikov A. et al. Journal of the american chemical society. 2014. Vol. 136. No. 28. P. 9818-9821.

Heme-carbonyl complexes are widely exploited for the insight they provide into the structural basis of function in heme-based proteins and enzymes, by revealing the nature of their bonded and nonbonded interactions with the protein. This report presents two novel results which, taken together, clearly establish a FeCO vibrational signature for crystallographically verified penta-coordination. First, anysotropy in the NRVS density of states for \nu_{Fe-C} and \delta_{FeCO} in oriented single crystals of [Fe(OEP)(CO)] clearly reveals that the Fe-C stretch occurs at higher frequency than the FeCO bend and considerably higher than any previously reported heme carbonyl. Second, DFT calculations on a series of heme carbonyls reveal that the frequency crossover occurs near the weak trans O-atom donor, furan. As \nu_{Fe-C} occurs at lower frequencies than \delta_{FeCO} in all heme protein carbonyls reported to date, the results reported herein suggest that they are all hexacoordinate.

Added: Mar 14, 2016
Article
Sawada T., Petrov A. A. Journal of Neurophysiology. 2017. Vol. 118. P. 3051-3091.

This is a review study.  The physiological responses of simple and complex cells in the primary visual cortex (V1) have been studied extensively and modeled at different levels. At the functional level, the divisive normalization model (DNM; Heeger DJ. Vis Neurosci 9: 181–197, 1992) has accounted for a wide range of single-cell recordings in terms of a combination of linear filtering, nonlinear rectification, and divisive normalization. We propose standardizing the formulation of the DNM and implementing it in software that takes static grayscale images as inputs and produces firing rate responses as outputs. We also review a comprehensive suite of 30 empirical phenomena and report a series of simulation experiments that qualitatively replicate dozens of key experiments with a standard parameter set consistent with physiological measurements. This systematic approach identifies novel falsifiable predictions of the DNM. We show how the model simultaneously satisfies the conflicting desiderata of flexibility and falsifiability. Our key idea is that, while adjustable parameters are needed to accommodate the diversity across neurons, they must be fixed for a given individual neuron. This requirement introduces falsifiable constraints when this single neuron is probed with multiple stimuli. We also present mathematical analyses and simulation experiments that explicate some of these constraints.

Added: Sep 29, 2017
Article
Dubois J., Dehaene-Lambertz G., Kulikova S. et al. Neuroscience. 2015. Vol. 276. P. 48-71.

Studying how the healthy human brain develops is important to understand early pathological mechanisms and to assess the influence of fetal or perinatal events on later life. Brain development relies on complex and intermingled mechanisms especially during gestation and first post-natal months, with intense interactions between genetic, epigenetic and environmental factors. Although the baby's brain is organized early on, it is not a miniature adult brain: regional brain changes are asynchronous and protracted, i.e. sensory-motor regions develop early and quickly, whereas associative regions develop later and slowly over decades. Concurrently, the infant/child gradually achieves new performances, but how brain maturation relates to changes in behavior is poorly understood, requiring non-invasive in vivo imaging studies such as magnetic resonance imaging (MRI). Two main processes of early white matter development are reviewed: (1) establishment of connections between brain regions within functional networks, leading to adult-like organization during the last trimester of gestation, (2) maturation (myelination) of these connections during infancy to provide efficient transfers of information. Current knowledge from post-mortem descriptions and in vivo MRI studies is summed up, focusing on T1- and T2-weighted imaging, diffusion tensor imaging, and quantitative mapping of T1/T2 relaxation times, myelin water fraction and magnetization transfer ratio.

Added: Oct 22, 2015
Article
Blythe D., Haufe S., Müller K. et al. Neuroimage. 2014. Vol. 99. No. 1. P. 377-387.

Although the long-range temporal correlation (LRTC) of the amplitude fluctuations of neuronal EEG/MEG oscillations is widely acknowledged, the majority of studies to date have been performed in sensor space, disregarding the mixing effects implied by volume conduction and confounding noise. While the effect of mixing on the evaluation of evoked responses and connectivity measures has been extensively studied, there are, to date, no studies reporting on the differences in the values of the estimated Hurst exponents when moving between sensor and source space representations of the multivariate data or on the effect of noise. Such differences, if not duly acknowledged, may lead to erroneous data interpretations. We show in simulations and in theory that measuring Hurst exponents in sensor space may lead to an incomplete picture of the LRTC properties of the underlying data and that noise may significantly bias the estimate of the Hurst exponent of the underlying signal. Moreover, these predictions are confirmed in real data, where we analyze the amplitude dynamics of neuronal oscillations in the resting state from EEG data. By moving either to an independent components representation or to a source representation which maximizes the signal to noise ratio in the alpha frequency range, we observe greater variance, skewness and kurtosis over measured Hurst exponents than in sensor space. We confirm the suitability of conventional source separation methodology by introducing a novel algorithm HeMax which obtains a source maximizing the Hurst exponent in the amplitude dynamics of narrow band oscillations. Our findings imply that the long-range correlative properties of the EEG should be studied in source space, in such a way that the SNR is maximized, or at least with spatial decomposition techniques approximating source activities, rather than in sensor space.

Added: Feb 17, 2015
Article
Solomina O., Kuznetsova V., Cook E. et al. Climate Dynamics. 2020. Vol. 54. No. 3-4. P. 2317-2335.

We present the European Russia Drought Atlas (ERDA) that covers the East European Plain to the Ural Mountains from 1400–2016 CE. Like the Old World Drought Atlas (OWDA) for the Euro-Mediterranean region, the ERDA is a one-half degree gridded reconstruction of summer Palmer Drought Severity Indices estimated from a network of annual tree-ring chronologies. Ensemble point-by-point regression is used to generate the ERDA with the identical protocols used for developing the OWDA. Split calibration/validation tests of the ERDA indicate that it has significant skill over most of its domain and is much more skillful than the OWDA where they overlap in the western part of ERDA domain. Comparisons to historical droughts over European Russia additionally support the ERDA’s overall validity. The ERDA has been spatially smoothed and infilled using a local regression method to yield a spatially complete drought atlas back to 1400 CE. EOF analysis indicates that there are three principal modes of hydroclimatic variability in the ERDA. After Varimax rotation, these modes correlate significantly with independent climate data sets extending back to the late nineteenth century in a physically interpretable way and relate to atmospheric circulation dynamics of droughts and heatwaves over European Russia based on more recent instrumental data.

Added: Mar 24, 2020
Article
Shchekotikhin A., Glazunova V.A., Dezhenkova L. et al. European Journal of Medicinal Chemistry. 2011. Vol. 46. No. 1. P. 423-428.

We developed the synthesis of a series of furan-fused tetracyclic analogues of the antitumor agent ametantrone. The reactions included nucleophilic substitution of propoxy groups in 4,11-dipropoxyanthra[2,3-b]furan-5,10-diones with ethylenediamines, producing the derivatives of 4,11-diaminoanthra[2,3-b] furan-5,10-dione in good yields. Studies of anti-proliferative activity on a panel of mammalian tumor cell lines demonstrated that anthra[2,3-b]furan-5,10- diones were the most potent derivatives among heteroarene-fused ametantrone analogues with one heteroatom. We identified several compounds that evoked a growth inhibitory effect at submicromolar concentrations. The anthra[2,3-b]furan-5,10-dione 9 with distal methylamino groups was markedly potent against drug-resistant cell lines with P-glycoprotein overexpression or p53 gene deletion. Furthermore, this derivative attenuated in vitro topoisomerase I-mediated DNA uncoiling at low micromolar concentrations. These results demonstrate that anthrafurandiones are a new class of heterocyclic anthraquinone derivatives with the properties potentially valuable for anticancer therapy.

 

 

Added: Jul 14, 2015
Article
Büdenbender M., Golubchikov O. International Journal of Housing Policy. 2017. Vol. 17. No. 1. P. 75-96.

The article problematises the role of real estate in geopolitical circulations. The internationalisation of real estate increases mutual dependencies and vulnerabilities between nation states and, therefore, calls for a better appreciation of the geopolitical externalities and exteriorities of real estate. The article brings together disjoint bodies of literature on real estate globalisation, assemblage theory, and international relations to show how real estate is a case of the geopolitics of the multiple – geopolitics that is being assembled by diverse and distributed actors, discourses, and materialities representing the contingent and emergent formation of connections and considerations, which affect the ways how foreign relations are negotiated today. The argument is substantiated by considering several dimensions of the real estate/geopolitics nexus: (1) external influences over domestic real estate markets; (2) the implications of outward real estate investment; and (3) state-led mega-projects conveying externally the power of the state. These dimensions are considered empirically in the context of the renewed geopolitical tensions between a resurgent Russia and the West. Overall, the article calls for a better positioning of real estate in the conceptualisations of soft power, state power, and geopolitics.

Added: Dec 11, 2016
Article
Vlassov V. JAMA Oncology. 2015. Vol. 1. No. 4. P. 505-527.

ABSTRACT

Cancer is among the leading causes of death worldwide. Current estimates of cancer burden in individual countries and regions are necessary to inform local cancer control strategies.

OBJECTIVE

To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 28 cancers in 188 countries by sex from 1990 to 2013.

EVIDENCE REVIEW

The general methodology of the Global Burden of Disease (GBD) 2013 study was used. Cancer registries were the source for cancer incidence data as well as mortality incidence (MI) ratios. Sources for cause of death data include vital registration system data, verbal autopsy studies, and other sources. The MI ratios were used to transform incidence data to mortality estimates and cause of death estimates to incidence estimates. Cancer prevalence was estimated using MI ratios as surrogates for survival data; YLDs were calculated by multiplying prevalence estimates with disability weights, which were derived from population-based surveys; YLLs were computed by multiplying the number of estimated cancer deaths at each age with a reference life expectancy; and DALYs were calculated as the sum of YLDs and YLLs.

FINDINGS

In 2013 there were 14.9 million incident cancer cases, 8.2 million deaths, and 196.3 million DALYs. Prostate cancer was the leading cause for cancer incidence (1.4 million) for men and breast cancer for women (1.8 million). Tracheal, bronchus, and lung (TBL) cancer was the leading cause for cancer death in men and women, with 1.6 million deaths. For men, TBL cancer was the leading cause of DALYs (24.9 million). For women, breast cancer was the leading cause of DALYs (13.1 million). Age-standardized incidence rates (ASIRs) per 100,000 and age-standardized death rates (ASDRs) per 100,000 for both sexes in 2013 were higher in developing vs developed countries for stomach cancer (ASIR, 17 vs 14; ASDR, 15 vs 11), liver cancer (ASIR, 15 vs 7; ASDR, 16 vs 7), esophageal cancer (ASIR, 9 vs 4; ASDR, 9 vs 4), cervical cancer (ASIR, 8 vs 5; ASDR, 4 vs 2), lip and oral cavity cancer (ASIR, 7 vs 6; ASDR, 2 vs 2), and nasopharyngeal cancer (ASIR, 1.5 vs 0.4; ASDR, 1.2 vs 0.3). Between 1990 and 2013, ASIRs for all cancers combined (except nonmelanoma skin cancer and Kaposi sarcoma) increased by more than 10% in 113 countries and decreased by more than 10% in 12 of 188 countries.

CONCLUSIONS AND RELEVANCE

Cancer poses a major threat to public health worldwide, and incidence rates have increased in most countries since 1990. The trend is a particular threat to developing nations with health systems that are ill-equipped to deal with complex and expensive cancer treatments. The annual update on the global burden of cancer will provide all stakeholders with timely estimates to guide policy efforts in cancer prevention, screening, treatment, and palliation.

 

Added: Jun 7, 2015
Article
Vlassov V.V. The Lancet. 2016. Vol. 388. No. 10049. P. 1081-1088.

Background

With recent improvements in vaccines and treatments against viral hepatitis, an improved understanding of the burden of viral hepatitis is needed to inform global intervention strategies. We used data from the Global Burden of Disease (GBD) Study to estimate morbidity and mortality for acute viral hepatitis, and for cirrhosis and liver cancer caused by viral hepatitis, by age, sex, and country from 1990 to 2013.

Methods

We estimated mortality using natural history models for acute hepatitis infections and GBD's cause-of-death ensemble model for cirrhosis and liver cancer. We used meta-regression to estimate total cirrhosis and total liver cancer prevalence, as well as the proportion of cirrhosis and liver cancer attributable to each cause. We then estimated cause-specific prevalence as the product of the total prevalence and the proportion attributable to a specific cause. Disability-adjusted life-years (DALYs) were calculated as the sum of years of life lost (YLLs) and years lived with disability (YLDs).

Findings

Between 1990 and 2013, global viral hepatitis deaths increased from 0·89 million (95% uncertainty interval [UI] 0·86–0·94) to 1·45 million (1·38–1·54); YLLs from 31·0 million (29·6–32·6) to 41·6 million (39·1–44·7); YLDs from 0·65 million (0·45–0·89) to 0·87 million (0·61–1·18); and DALYs from 31·7 million (30·2–33·3) to 42·5 million (39·9–45·6). In 2013, viral hepatitis was the seventh (95% UI seventh to eighth) leading cause of death worldwide, compared with tenth (tenth to 12th) in 1990.

Interpretation

Viral hepatitis is a leading cause of death and disability worldwide. Unlike most communicable diseases, the absolute burden and relative rank of viral hepatitis increased between 1990 and 2013. The enormous health loss attributable to viral hepatitis, and the availability of effective vaccines and treatments, suggests an important opportunity to improve public health.

Added: Jul 9, 2016
Article
Golubchikov O., Badyina A., Makhrova A. Urban Studies. 2014. Vol. 51. No. 4. P. 617-633.

This paper conceptualises post-socialist urban economic geographies through the notion of hybrid spatialities that emerge from the mutual embeddedness of neoliberalism and socialist legacies. While the dismantling of state socialism was a massive moment towards the exacerbation of uneven development, ironically it is the socialist-era spatial legacy that has become the single major differentiating factor for the economic status of cities. This superficial overdetermination, however, masks the root causes of uneven development that must be seen in the logic of capitalism and its attendant practices which subsume legacy, recode its meaning, and recast the formerly equalitarian spaces as an uneven spatial order. The authors argue that the socialist legacy, rather than being an independent carrier of history, has been alienated from its history to become an infrastructure of neoliberalisation, conducive to capitalist process. The paper draws specifically on the experiences of Russia, although its reflections should reverberate much more broadly.

Added: Oct 9, 2014
Article
Andres L., Golubchikov O. International Journal of Urban and Regional Research. 2016. Vol. 40. No. 4. P. 757-775.

Despite the burgeoning literature on creative cities, seldom explored is the context of cities rich in cultural capital but more orthodox in their approach to preserving the autonomy of culture. This article discusses the status of artistic spaces occupying abandoned industrial premises (‘creative brownfields') in historic cities that traditionally shape their policies around prestigious cultural institutions (‘cities of high culture'). Based on comparative insights from St Petersburg and Lausanne, the article explores the relations and tensions between mainstream cultural governance and creative brownfields. While there is no lack of creative brownfields in these cities, their wider urban impact is found to be marginal; moreover, these sites represent dispersed instances of temporary occupations rather than situated clusters of creative actors. More than coincidental, this (lack of) spatialization is argued to result from a particular governmentality—that of high culture—which disregards, rather than promotes, spaces of alternative cultural governance. The article conceptualizes creative brownfields in cities of high culture as the ‘soft infrastructure' of cultural production, in contrast with those in ‘creative cities' as the ‘hard infrastructure' of urban production. The article also calls for a recognition of the local context of regulation and accumulation in understanding the cultural/urban interplay.

Added: Dec 11, 2016