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Article

A role of local VTA GABAergic neurons in mediating dopamine neuron response to nicotine

BMC Neuroscience. 2015. Vol. 16. No. 1. P. 137.
Morozova E., Myroshnychenko M., Rooy M. E., Gutkin B., Lapish C., Kuzntesov A.

The local circuitry of the tegmental area (VTA) consists primarily of dopamine (DA) and GABA neurons. Interactions between DA and GABA neurons are critical for regulating DA neuron activity, and thus DA efflux throughout the brain. One striking example that demonstrates the significance of local interactions between DA and GABA neurons is related to nicotine reinforcement.