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Article

Spike Frequency Adaptation

Scholarpedia. 2014. Vol. 9. No. 2. P. 30643.
Zeldenrust F., Gutkin B.

When stimulated with a square pulse or step, many neurons show a reduction in the firing frequency of their spike response following an initial increase (Fig. Figure 1 B). This phenomenon is called spike-frequency adaptation. In this article several cellular mechanisms leading to spike-frequency adaptation and its consequences will be discussed.